Drug Combination Details

General Information of the Combination (ID: C80627)
Name Tanshinone IIA   NP Info  + Atorvastatin   Drug Info 
Structure +
Disease
Atherosclerosis [ICD-11: BD40]
Investigative [1]
Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally
    α. Enhancing Drug Efficacy by This Combination
                 Achieving Therapeutic Synergy     Click to Show/Hide
                    Experiment 1 Reporting the Effect of This Combination [1]
                    In-vivo Model Six-week old male ApoE KO mice were used in this study.
                    Experimental
                    Result(s)		 Tan in conjunction with Ato represents an effective combination therapy to comprehensively combat atherogenesis in ApoE / mice by reducing plaque size and stabilizing vulnerable atheromatous plaques.
References
Reference 1 Effectiveness of combination therapy of atorvastatin and non lipid-modifying tanshinone IIA from Danshen in a mouse model of atherosclerosis. Int J Cardiol. 2014 Jul 1;174(3):878-80.
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