Drug Combination Details
| General Information of the Combination (ID: C83484) | |||||
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| Name | Retinol | + | Oxacillin + Ampicillin | ||
| Click to Show/Hide the Each NP or Drug Information of This Combination | |||||
| Name | Retinol NP Info | Drug Info | |||
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| Name | Drug Info | ||||
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| Disease |
Staphylococcus infection
[ICD-11: 1C41]
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Investigative | [1] | ||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
|---|---|---|---|---|---|---|
| α. Enhancing Drug Efficacy by This Combination | ||||||
| Achieving Therapeutic Synergy | Click to Show/Hide | |||||
| Experiment 1 Reporting the Effect of This Combination | [1] | |||||
| In-vitro Model | Staphylococcus aureus strains | Microorganism model | Staphylococcus aureus | |||
| Staphylococcus aureus ATCC 33591 | Microorganism model | Staphylococcus aureus | ||||
| Staphylococcus aureus ATCC 25923 | Microorganism model | Staphylococcus aureus | ||||
| Experimental
Result(s) |
Rhein in combination with AM or OX could lead to the development of new combinations of antibiotics against MRSA infection. | |||||
| References | ||||
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| Reference 1 | Synergistic effect of rhein in combination with ampicillin or oxacillin against methicillin-resistant Staphylococcus aureus. Exp Ther Med. 2012 Apr;3(4):608-612. | |||
