Drug Combination Details
| General Information of the Combination (ID: C86585) | |||||
|---|---|---|---|---|---|
| Name | Colistin NP Info | + | Eravacycline Drug Info | ||
| Structure |
|
+ |
|
||
| Disease |
Pneumonia
[ICD-11: CA40]
|
Investigative | [1] | ||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
|---|---|---|---|---|---|---|
| α. Enhancing Drug Efficacy by This Combination | ||||||
| Achieving Therapeutic Synergy | Click to Show/Hide | |||||
| Experiment 1 Reporting the Effect of This Combination | [1] | |||||
| In-vitro Model | Acinetobacter baumannii | Microorganism model | Acinetobacter baumannii | |||
| Experimental
Result(s) |
Eravacycline and colistin combination may be a potential therapeutic option for the treatment of CRAB related infections. | |||||
| References | ||||
|---|---|---|---|---|
| Reference 1 | In vitro activity of eravacycline in combination with colistin against carbapenem-resistant A. baumannii isolates. J Antibiot (Tokyo). 2019 Aug;72(8):600-604. | |||