Drug Combination Details

General Information of the Combination (ID: C87549)
Name Fosfomycin   NP Info  + Rifampicin   Drug Info 
Structure +
Disease
Staphylococcus infection [ICD-11: 1C41]
Investigative [1]
Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally
    α. Enhancing Drug Efficacy by This Combination
                 Achieving Therapeutic Synergy     Click to Show/Hide
                    Experiment 1 Reporting the Effect of This Combination [1]
                    In-vivo Model Clinical trial
                    Experimental
                    Result(s)		 In patients with implanted foreign devices, combination therapy was associated with a better long-term outcome.
References
Reference 1 Combination therapy with rifampicin or fosfomycin in patients with Staphylococcus aureus bloodstream infection at high risk for complications or relapse: results of a large prospective observational cohort. J Antimicrob Chemother. 2020 Aug 1;75(8):2282-2290.
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