Drug Combination Details
| General Information of the Combination (ID: C88589) | |||||
|---|---|---|---|---|---|
| Name | Metformin NP Info | + | Glibenclamide Drug Info | ||
| Structure |
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+ |
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| Disease |
Gestational diabetes mellitus
[ICD-11: JA63]
|
Phase 4 | [1] | ||
|
Type 2 diabetes mellitus
[ICD-11: 5A11]
|
Investigative | [2] | |||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
|---|---|---|---|---|---|---|
| α. Enhancing Drug Efficacy by This Combination | ||||||
| Achieving Therapeutic Synergy | Click to Show/Hide | |||||
| Experiment 1 Reporting the Effect of This Combination | [2] | |||||
| In-vivo Model | Clinical Trial | |||||
| Experimental
Result(s) |
Combination of glibenclamide-metformin should be considered in patients, without renal or cardiovascular impairment, who are not controlled on monotherapy alone. | |||||