Drug Combination Details

General Information of the Combination (ID: C88607)
Name Oxyprogesterone caproate   NP Info  + Tamoxifen   Drug Info 
Structure +
Disease
Uterine cancer [ICD-11: 2C76]
Investigative [1]
Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally
    α. Enhancing Drug Efficacy by This Combination
                 Achieving Therapeutic Synergy     Click to Show/Hide
                    Experiment 1 Reporting the Effect of This Combination [1]
                    Experimental
                    Result(s)		 Oxyprogesterone caproate (OPC) administered preoperatively and after surgical and combined therapy from 6 up to 36 months increased the corrected survival rates as compared with that in patients who did not receive hormone treatment.
References
Reference 1 Favourable influence of adjuvant hormone therapy by oxyprogesterone caproate (OPC) and by its combination with tamoxifen on 5-year survival rate of surgical and combined treatment of primary endometrial carcinoma patients. Eur J Gynaecol Oncol. 1993;14(2):150-3.
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