Drug Combination Details
| General Information of the Combination (ID: C90798) | |||||
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| Name | Pentostatin + Cladribine | + | Rituximab | ||
| Click to Show/Hide the Each NP or Drug Information of This Combination | |||||
| Name | Pentostatin NP Info | Drug Info | |||
| Structure |
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| Name | Cladribine NP Info | ||||
| Structure |
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| Disease |
Chronic lymphocytic leukaemia
[ICD-11: 2A82]
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Investigative | [1] | ||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
|---|---|---|---|---|---|---|
| α. Enhancing Drug Efficacy by This Combination | ||||||
| Achieving Therapeutic Synergy | Click to Show/Hide | |||||
| Experiment 1 Reporting the Effect of This Combination | [1] | |||||
| Experimental
Result(s) |
The combination of a purine analog with rituximab was safe and effective for patients with recurrent HCL. | |||||
| References | ||||
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| Reference 1 | Rituximab with pentostatin or cladribine: an effective combination treatment for hairy cell leukemia after disease recurrence. Leuk Lymphoma. 2011 Jun;52 Suppl 2:75-8. | |||
