Drug Combination Details
| General Information of the Combination (ID: C91293) | |||||
|---|---|---|---|---|---|
| Name | Chrysin NP Info | + | Epirubicin Drug Info | ||
| Structure |
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+ |
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| Disease |
Breast cancer
[ICD-11: 2C60]
|
Investigative | [1] | ||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
|---|---|---|---|---|---|---|
| α. Enhancing Drug Efficacy by This Combination | ||||||
| Achieving Therapeutic Synergy | Click to Show/Hide | |||||
| Experiment 1 Reporting the Effect of This Combination | [1] | |||||
| In-vitro Model | MDA-MB-231 | CVCL_0062 | Breast adenocarcinoma | Homo sapiens | ||
| L5178 | Mouse leukemia | Rattus norvegicus | ||||
| Experimental
Result(s) |
Chrysin synergistically enhanced the effect of epirubicin. | |||||
| References | ||||
|---|---|---|---|---|
| Reference 1 | In vitro search for synergy between flavonoids and epirubicin on multidrug-resistant cancer cells. In Vivo. Mar-Apr 2005;19(2):367-74. | |||
