Drug Combination Details
| General Information of the Combination (ID: C91487) | |||||
|---|---|---|---|---|---|
| Name | Choline NP Info | + | Aspirin Drug Info | ||
| Structure |
|
+ |
|
||
| Disease |
Discovery agent
[ICD-11: N.A.]
|
Investigative | [1] | ||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
|---|---|---|---|---|---|---|
| α. Enhancing Drug Efficacy by This Combination | ||||||
| Achieving Therapeutic Synergy | Click to Show/Hide | |||||
| Experiment 1 Reporting the Effect of This Combination | [1] | |||||
| In-vivo Model | Eight-week-old male mice were induced of carrageenan paw edema. | |||||
| Experimental
Result(s) |
Combined choline and aspirin therapy represented a significant synergistic interaction in attenuating acute inflammatory response. | |||||
| References | ||||
|---|---|---|---|---|
| Reference 1 | Synergistic interaction between choline and aspirin against acute inflammation induced by carrageenan and lipopolysaccharide. Int Immunopharmacol. 2014 May;20(1):229-37. | |||
