Drug Combination Details
| General Information of the Combination (ID: C92656) | |||||
|---|---|---|---|---|---|
| Name | Vincristine NP Info | + | Dipyridamole Drug Info | ||
| Structure |
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+ |
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| Disease |
Acute lymphoblastic leukemia
[ICD-11: 2B33]
|
Investigative | [1] | ||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
|---|---|---|---|---|---|---|
| α. Enhancing Drug Efficacy by This Combination | ||||||
| Achieving Therapeutic Synergy | Click to Show/Hide | |||||
| Experiment 1 Reporting the Effect of This Combination | [1] | |||||
| In-vitro Model | MOLT-3 | CVCL_0624 | Adult T acute lymphoblastic leukemia | Homo sapiens | ||
| ML1 | CVCL_0436 | Adult acute myeloid leukemia | Homo sapiens | |||
| BL-TH | Burkitt's lymphoma | Homo sapiens | ||||
| Experimental
Result(s) |
Dipyridamole and vincristine combination showed synergistic inhibitory effects on the growth of human leukaemia and lymphoma cell lines. | |||||
| References | ||||
|---|---|---|---|---|
| Reference 1 | Synergistic inhibitory effects of dipyridamole and vincristine on the growth of human leukaemia and lymphoma cell lines. Br J Cancer. 1987 Oct;56(4):413-7. | |||
