Drug Combination Details
| General Information of the Combination (ID: C92668) | |||||
|---|---|---|---|---|---|
| Name | Salvianolic acid A NP Info | + | Latamoxef Drug Info | ||
| Structure |
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+ |
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| Disease |
Staphylococcus infection
[ICD-11: 1C41]
|
Investigative | [1] | ||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
|---|---|---|---|---|---|---|
| α. Enhancing Drug Efficacy by This Combination | ||||||
| Achieving Therapeutic Synergy | Click to Show/Hide | |||||
| Experiment 1 Reporting the Effect of This Combination | [1] | |||||
| In-vivo Model | Ten mice were challenged with 2 * 109 CFU S. aureus. | |||||
| Experimental
Result(s) |
The combination of salvianolic acid A with latamoxef completely protects mice against lethal pneumonia caused by methicillin-resistant Staphylococcus aureus. | |||||
