Drug Combination Details
| General Information of the Combination (ID: C94751) | |||||
|---|---|---|---|---|---|
| Name | Wedelolactone NP Info | + | Cisplatin Drug Info | ||
| Structure |
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+ |
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| Disease |
Cervical cancer
[ICD-11: 2C77]
|
Investigative | [1] | ||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
|---|---|---|---|---|---|---|
| α. Enhancing Drug Efficacy by This Combination | ||||||
| Achieving Therapeutic Synergy | Click to Show/Hide | |||||
| Experiment 1 Reporting the Effect of This Combination | [1] | |||||
| In-vitro Model | HeLa | CVCL_0030 | Endocervical adenocarcinoma | Homo sapiens | ||
| Experimental
Result(s) |
Sequential combination of cisplatin with wedelolactone showed synergistic antitumor effect in cervical cancer cells. | |||||
| References | ||||
|---|---|---|---|---|
| Reference 1 | Synergistic Cytotoxic Effect from Combination of Wedelolactone and Cisplatin in HeLa Cell Line: A Novel Finding. Drug Des Devel Ther. 2020 Sep 22;14:3841-3852. | |||
