Drug Combination Details
| General Information of the Combination (ID: C96554) | |||||
|---|---|---|---|---|---|
| Name | Methylglyoxal NP Info | + | Oseltamivir Drug Info | ||
| Structure |
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+ |
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| Disease |
Influenza
[ICD-11: 1E30]
|
Investigative | [1] | ||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
|---|---|---|---|---|---|---|
| α. Enhancing Drug Efficacy by This Combination | ||||||
| Achieving Therapeutic Synergy | Click to Show/Hide | |||||
| Experiment 1 Reporting the Effect of This Combination | [1] | |||||
| In-vitro Model | MDCK | CVCL_0422 | Healthy | Canis lupus familiaris | ||
| Experimental
Result(s) |
MGO has potent inhibitory activity against influenza viruses and also enhanced the effect of NA inhibitors. | |||||
| References | ||||
|---|---|---|---|---|
| Reference 1 | In vitro evaluation of synergistic inhibitory effects of neuraminidase inhibitors and methylglyoxal against influenza virus infection. Arch Med Res. 2015 Jan;46(1):8-16. | |||
