Drug Combination Details
| General Information of the Combination (ID: C99130) | |||||
|---|---|---|---|---|---|
| Name | Tropisetron NP Info | + | Fluvoxamine Drug Info | ||
| Structure |
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+ |
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| Disease |
Obsessive-compulsive disorder
[ICD-11: 6B20]
|
Investigative | [1] | ||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
|---|---|---|---|---|---|---|
| α. Enhancing Drug Efficacy by This Combination | ||||||
| Achieving Therapeutic Synergy | Click to Show/Hide | |||||
| Experiment 1 Reporting the Effect of This Combination | [1] | |||||
| Biological
Regulation |
Down-regulation | 5-HT content | ||||
| In-vivo Model | Clinical Trial | |||||
| Experimental
Result(s) |
This trial showed a significant efficacy for tropisetron over placebo in treatment of obsessive-compulsive disorder symptoms when added to fluvoxamine. | |||||
