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Drug Details

General Information of the Drug (ID: DR0417)
Name
Metformin
Synonyms
metformin 657-24-9 1,1-Dimethylbiguanide N,N-dimethylimidodicarbonimidic diamide Imidodicarbonimidic diamide, N,N-dimethyl-
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Molecular Type
Small molecule
Disease Non alcoholic fatty liver disease [ICD-11: DB92] Approved
Structure
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2D MOL

3D MOL

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Formula
C4H11N5
PubChem CID
4091
Canonical SMILES
CN(C)C(=N)N=C(N)N
InChI
InChI=1S/C4H11N5/c1-9(2)4(7)8-3(5)6/h1-2H3,(H5,5,6,7,8)
InChIKey
XZWYZXLIPXDOLR-UHFFFAOYSA-N
CAS Number
657-24-9;1115-70-4
ChEBI ID
CHEBI:6801
TTD Drug ID
D0D7LA
DrugBank ID
DB00331
Target and Pathway
Target(s) Sequestosome-1 p62 (SQSTM1)  Molecule Info 
Cite NPCDR
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Correspondence

X. N. Sun, Y. T. Zhang, Y. Zhou, X. C. Lian, L. L. Yan, T. Pan, T. Jin, H. Xie, Z. M. Liang, W. Q. Qiu, J. X. Wang, Z. R. Li, F. Zhu*, X. B. Sui*. NPCDR: natural product-based drug combination and its disease-specific molecular regulation. Nucleic Acids Research. 50(D1): 1324-1333 (2020). PMID: 34664659

Prof. Feng ZHU  (zhufeng@zju.edu.cn)

College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China


Prof. Xinbing SUI  (suilab@hznu.edu.cn)

School of Pharmacy and Department of Medical Oncology, the Affiliated Hospital of Hangzhou Normal University, Hangzhou Normal University, Hangzhou, China