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Natural Product (NP) Details

General Information of the NP (ID: NP1018)
Name
Nordihydroguaiaretic acid
Species Origin Nordihydroguaiaretic acid (Larrea tridentata) ...     Click to Show/Hide
Nordihydroguaiaretic acid (Larrea tridentata)
SuperKingdom: Eukaryota
Kingdom: Plantae
Phylum: Tracheophyta
Class: Magnoliopsida
Order: Zygophyllales
Family: Zygophyllaceae
Genus: Larrea
Species: L. tridentata
Disease Lung cancer [ICD-11: 2C25] Investigative
Structure
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2D MOL

3D MOL

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Formula
C18H22O4
PubChem CID
4534
Canonical SMILES
CC(CC1=CC(=C(C=C1)O)O)C(C)CC2=CC(=C(C=C2)O)O
InChI
InChI=1S/C18H22O4/c1-11(7-13-3-5-15(19)17(21)9-13)12(2)8-14-4-6-16(20)18(22)10-14/h3-6,9-12,19-22H,7-8H2,1-2H3
InChIKey
HCZKYJDFEPMADG-UHFFFAOYSA-N
CAS Number
500-38-9
ChEBI ID
CHEBI:7625
Target and Pathway
Target(s) Heme oxygenase 1  Molecule Info 
Cite NPCDR
Visitor Map
Correspondence

X. N. Sun, Y. T. Zhang, Y. Zhou, X. C. Lian, L. L. Yan, T. Pan, T. Jin, H. Xie, Z. M. Liang, W. Q. Qiu, J. X. Wang, Z. R. Li, F. Zhu*, X. B. Sui*. NPCDR: natural product-based drug combination and its disease-specific molecular regulation. Nucleic Acids Research. 50(D1): 1324-1333 (2020). PMID: 34664659

Prof. Feng ZHU  (zhufeng@zju.edu.cn)

College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China


Prof. Xinbing SUI  (suilab@hznu.edu.cn)

School of Pharmacy and Department of Medical Oncology, the Affiliated Hospital of Hangzhou Normal University, Hangzhou Normal University, Hangzhou, China