Natural Product (NP) Details
| General Information of the NP (ID: NP7659) | |||||
|---|---|---|---|---|---|
| Name |
Bovine lactoferrin
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| Species Origin | Milk vetch dwarf China alphasatellite ... | Click to Show/Hide | |||
| Milk vetch dwarf China alphasatellite | |||||
| Disease | Diarrhea [ICD-11: ME05] | Phase 2 | [1] | ||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
|---|---|---|---|---|---|---|
| α. A List of Drug(s) Whose Efficacy can be Enhanced by This NP | ||||||
| Penicillin G | Syphilis | Click to Show/Hide the Molecular Data of This Drug | ||||
| Achieving Therapeutic Synergy | Click to Show/Hide | |||||
| Representative Experiment Reporting the Effect of This Combination | [2] | |||||
| Detail(s) |
Combination Info
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| In-vivo Model | Nineteen late-lactating cows had all 4 mammary quarters individually inoculated (185 cfu) through the teat cistern with the PG-resistant Staph. Aureus SHY97-4320. | |||||
| Experimental
Result(s) |
BLF added to PG is an effective combination (i.e., 3- to 5-times higher cure rate) for the treatment of stable Staph. aureu infections highly resistant to beta-lactam antibiotics. | |||||
