Molecule Details

Natural Product(s) of This Target
1 Colchicine  NP Info  Approved Colchicum autumnale
Drug(s) of This Target
1 Cabazitaxel  Drug Info  Approved Breast cancer
2 Docetaxel  Drug Info  Approved Solid tumour/cancer
3 Vinorelbine  Drug Info  Approved Solid tumour/cancer
References
Reference 1 Vitamin K3 disrupts the microtubule networks by binding to tubulin: a novel mechanism of its antiproliferative activity. Biochemistry. 2009 Jul 28;48(29):6963-74.
Reference 2 Mullard A: 2010 FDA drug approvals. Nat Rev Drug Discov. 2011 Feb;10(2):82-5.
Reference 3 Docetaxel: a review of its use in metastatic breast cancer. Drugs. 2005;65(17):2513-31.
Reference 4 Vinca alkaloid and MDR1. Gan To Kagaku Ryoho. 2008 Jul;35(7):1086-9.