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Molecule Details

General Information of the Molecule
Name
Interferon-beta (IFNB1)
Synonyms
Interferon beta; IFNbeta; IFNB; IFN-beta; IFB; Fibroblast interferon
Gene Name
IFNB1
Gene ID
3456
Sequence
MTNKCLLQIALLLCFSTTALSMSYNLLGFLQRSSNFQCQKLLWQLNGRLEYCLKDRMNFD
IPEEIKQLQQFQKEDAALTIYEMLQNIFAIFRQDSSSTGWNETIVENLLANVYHQINHLK
TVLEEKLEKEDFTRGKLMSSLHLKRYYGRILHYLKAKEYSHCAWTIVRVEILRNFYFINR
LTGYLRN
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Function
Has antiviral, antibacterial and anticancer activities.
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Uniprot ID
IFNB_HUMAN
Pfam
PF00143
KEGG ID
hsa3456
TTD ID
T02808
Natural Product(s) of This Target
1 Bufalin  NP Info  Investigative Bufo gargarizans
References
Reference 1 Cardiac glycosides are potent inhibitors of interferon-Beta gene expression. Nat Chem Biol. 2011 Jan;7(1):25-33.
Cite NPCDR
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Correspondence

X. N. Sun, Y. T. Zhang, Y. Zhou, X. C. Lian, L. L. Yan, T. Pan, T. Jin, H. Xie, Z. M. Liang, W. Q. Qiu, J. X. Wang, Z. R. Li, F. Zhu*, X. B. Sui*. NPCDR: natural product-based drug combination and its disease-specific molecular regulation. Nucleic Acids Research. 50(D1): 1324-1333 (2020). PMID: 34664659

Prof. Feng ZHU  (zhufeng@zju.edu.cn)

College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China


Prof. Xinbing SUI  (hzzju@hznu.edu.cn)

School of Pharmacy and Department of Medical Oncology, the Affiliated Hospital of Hangzhou Normal University, Hangzhou Normal University, Hangzhou, China