Molecule Details
| General Information of the Molecule | ||||
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| Name |
NADPH oxidase (NOX)
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| Function |
NOH-1S is a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes and other tissues. It participates in the regulation of cellular pH and is blocked by zinc. NOH-1L is a pyridine nucleotide-dependent oxidoreductase that generates superoxide and might conduct H(+) ions as part of its electron transport mechanism, whereas NOH-1S does not contain an electron transport chain.
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| Uniprot ID |
NOUNIPROTAC
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| TTD ID | ||||
| Natural Product(s) of This Target | ||||
|---|---|---|---|---|
| 1 | Sinomenine | NP Info | Discontinued in Phase 2 | Sinomenium |
| Drug(s) of This Target | ||||
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| 1 | Benfotiamine | Drug Info | Phase 4 | Substance abuse |