Molecule Details

Drug(s) of This Target
1 Capecitabine  Drug Info  Approved Colorectal cancer
2 Pemetrexed  Drug Info  Approved Pleural mesothelioma
3 Raltitrexed  Drug Info  Approved Rectum cancer
References
Reference 1 UGT1A7 and UGT1A9 polymorphisms predict response and toxicity in colorectal cancer patients treated with capecitabine/irinotecan. Clin Cancer Res. 2005 Feb 1;11(3):1226-36.
Reference 2 Updated clinical information on multitargeted antifolates in lung cancer. Clin Lung Cancer. 2009 Mar;10 Suppl 1:S35-40.
Reference 3 DNA damage and homologous recombination signaling induced by thymidylate deprivation. Biochem Pharmacol. 2008 Oct 15;76(8):987-96.