Molecule Details
| General Information of the Molecule | ||||
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| Name |
Interleukin-20 receptor alpha (IL20RA)
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| Synonyms |
IL-20 receptor subunit alpha; IL-20R-alpha; IL-20RA; Cytokine receptor class-II member 8; Cytokine receptor family 2 member 8; CRF2-8; IL-20R1; ZcytoR7
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| Gene Name |
IL20RA
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| Gene ID | ||||
| Sequence |
MRAPGRPALRPLPLPPLLLLLLAAPWGRAVPCVSGGLPKPANITFLSINMKNVLQWTPPE
GLQGVKVTYTVQYFIYGQKKWLNKSECRNINRTYCDLSAETSDYEHQYYAKVKAIWGTKC SKWAESGRFYPFLETQIGPPEVALTTDEKSISVVLTAPEKWKRNPEDLPVSMQQIYSNLK YNVSVLNTKSNRTWSQCVTNHTLVLTWLEPNTLYCVHVESFVPGPPRRAQPSEKQCARTL KDQSSEFKAKIIFWYVLPVSITVFLFSVMGYSIYRYIHVGKEKHPANLILIYGNEFDKRF FVPAEKIVINFITLNISDDSKISHQDMSLLGKSSDVSSLNDPQPSGNLRPPQEEEEVKHL GYASHLMEIFCDSEENTEGTSLTQQESLSRTIPPDKTVIEYEYDVRTTDICAGPEEQELS LQEEVSTQGTLLESQAALAVLGPQTLQYSYTPQLQDLDPLAQEHTDSEEGPEEEPSTTLV DWDPQTGRLCIPSLSSFDQDSEGCEPSEGDGLGEEGLLSRLYEEPAPDRPPGENETYLMQ FMEEWGLYVQMEN Click to Show/Hide
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| Function |
The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL20RA/IL10RB dimer is a receptor for IL26.
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| Uniprot ID | ||||
| Pfam | ||||
| KEGG ID | ||||
| Drug(s) of This Target | ||||
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| 1 | GC-SF | Drug Info | Approved | Acute myelogenous leukemia |
| References | ||||
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| Reference 1 | IL-24: A new player in the pathogenesis of pro-inflammatory and allergic skin diseases. Allergol Int. 2020 Jul;69(3):405-411. | |||