Molecule Details
| General Information of the Molecule | ||||
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| Name |
Bacterial Listeriolysin regulatory (Bact prfA)
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| Gene Name |
prfA
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| Gene ID | ||||
| Sequence |
MNAQAEEFKKYLETNGIKPKQFHKKELIFNQWDPQEYCIFLYDGITKLTSISENGTIMNL
QYYKGAFVIMSGFIDTETSVGYYNLEVISEQATAYVIKINELKELLSKNLTHFFYVFQTL QKQVSYSLAKFNDFSINGKLGSICGQLLILTYVYGKETPDGIKITLDNLTMQELGYSSGI AHSSAVSRIISKLKQEKVIVYKNSCFYVQNLDYLKRYAPKLDEWFYLACPATWGKLN Click to Show/Hide
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| Function |
Positively regulates expression of listeriolysin, of 1-phosphadidylinositol phosphodiesterase (PI-PLC) and other virulence factors.
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| Uniprot ID | ||||
| Pfam | ||||
| KEGG ID | ||||
| Drug(s) of This Target | ||||
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| 1 | HSV-TK/GCV | Drug Info | Phase 2 | Ovarian cancer |
| References | ||||
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| Reference 1 | Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. | |||