Molecule Details
| General Information of the Molecule | ||||
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| Name |
Dopamine D3 receptor (D3R)
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| Synonyms |
D(3) dopamine receptor
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| Gene Name |
DRD3
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| Gene ID | ||||
| Sequence |
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERAL
QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTV CSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQ QTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRK LSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHV SPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC Click to Show/Hide
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| Function |
Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. Promotes cell proliferation.
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| Uniprot ID | ||||
| TC Number | ||||
| Pfam | ||||
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| Drug(s) of This Target | ||||
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| 1 | FTY720 | Drug Info | Phase 1 | Psychoactive substances use disorder |
| References | ||||
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| Reference 1 | Clinical pipeline report, company report or official report of GlaxoSmithKline (2009). | |||