Molecule Details

Natural Product(s) of This Target
1 Apigenin  NP Info  Investigative Psilotum nudum
2 Biochanin A  NP Info  Investigative Dalbergia volubilis
3 Chrysin  NP Info  Investigative Tripterygium wilfordii
4 Exemestane  NP Info  Approved Homo sapiens
5 Naringenin  NP Info  Phase 1 Potentilla discolor
Drug(s) of This Target
1 BMS-228987  Drug Info  Investigative Breast cancer
2 Germacrone  Drug Info  Investigative Idiopathic pulmonary fibrosis
3 Letrozole  Drug Info  Approved Breast cancer
References
Reference 1 Pharmacophore modeling strategies for the development of novel nonsteroidal inhibitors of human aromatase (CYP19). Bioorg Med Chem Lett. 2010 May 15;20(10):3050-64.
Reference 2 Aromatase inhibitors--theoretical concept and present experiences in the treatment of endometriosis. Zentralbl Gynakol. 2003 Jul-Aug;125(7-8):247-51.
Reference 3 A review on biological sources, chemistry and pharmacological activities of pinostrobin. Nat Prod Res. 2016 Sep;30(18):2017-27.
Reference 4 Atamestane, a new aromatase inhibitor for the management of benign prostatic hyperplasia. J Androl. 1991 Nov-Dec;12(6):403-14.