Molecule Details
| General Information of the Molecule | ||||
|---|---|---|---|---|
| Name |
Preproendothelin-1 (EDN1)
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| Synonyms |
Endothelin-1; Preproendothelin-1; PPET1
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| Gene Name |
EDN1
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| Gene ID | ||||
| Sequence |
MDYLLMIFSLLFVACQGAPETAVLGAELSAVGENGGEKPTPSPPWRLRRSKRCSCSSLMD
KECVYFCHLDIIWVNTPEHVVPYGLGSPRSKRALENLLPTKATDRENRCQCASQKDKKCW NFCQAGKELRAEDIMEKDWNNHKKGKDCSKLGKKCIYQQLVRGRKIRRSSEEHLRQTRSE TMRNSVKSSFHDPKLKGKPSRERYVTHNRAHW Click to Show/Hide
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| Function |
Endothelins are endothelium-derived vasoconstrictor peptides.
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| Uniprot ID | ||||
| Pfam | ||||
| TTD ID | ||||
| Drug(s) of This Target | ||||
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| 1 | Tetramethylpyrazine | Drug Info | Discontinued in Phase 2 | Dissociative neurological symptom disorder |