Molecule Details
| General Information of the Molecule | ||||
|---|---|---|---|---|
| Name |
Melatonin receptor type 1A (MTNR1A)
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| Synonyms |
Mel1a receptor; Mel1AR; Mel-1A-R
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| Gene Name |
MTNR1A
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| Sequence |
MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRN
AGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITG IAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFA QSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTM FVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQ NFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV Click to Show/Hide
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| Function |
Likely to mediate the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity. High affinity receptor for melatonin.
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| Uniprot ID | ||||
| TTD ID | ||||
| Natural Product(s) of This Target | ||||
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| 1 | Melatonin | NP Info | Approved | Homo sapiens |