Molecule Details
| General Information of the Molecule | ||||
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| Name |
Glucose-dependent insulinotropic receptor (GPR119)
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| Synonyms |
GPR119; G-protein coupled receptor 119
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| Gene Name |
GPR119
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| Gene ID | ||||
| Sequence |
MESSFSFGVILAVLASLIIATNTLVAVAVLLLIHKNDGVSLCFTLNLAVADTLIGVAISG
LLTDQLSSPSRPTQKTLCSLRMAFVTSSAAASVLTVMLITFDRYLAIKQPFRYLKIMSGF VAGACIAGLWLVSYLIGFLPLGIPMFQQTAYKGQCSFFAVFHPHFVLTLSCVGFFPAMLL FVFFYCDMLKIASMHSQQIRKMEHAGAMAGGYRSPRTPSDFKALRTVSVLIGSFALSWTP FLITGIVQVACQECHLYLVLERYLWLLGVGNSLLNPLIYAYWQKEVRLQLYHMALGVKKV LTSFLLFLSARNCGPERPRESSCHIVTISSSEFDG Click to Show/Hide
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| Function |
Receptor for the endogenous fatty-acid ethanolamide oleoylethanolamide (OEA) and lysophosphatidylcholine (LPC). Functions as a glucose-dependent insulinotropic receptor. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Seems to act through a G(s) mediated pathway.
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| Uniprot ID | ||||
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| Drug(s) of This Target | ||||
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| 1 | MG132 | Drug Info | Investigative | Lung cancer |
| 2 | N-palmitoylethanolamine | Drug Info | Approved | Attention deficit hyperactivity disorder |