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Molecule Details

General Information of the Molecule
Name
Cytochrome bc1 complex (Complex III)
Synonyms
Electron transport complex III; Cytochrome bc1 complex; CoQH2-cytochrome c reductase
Gene Name
CYC1-MT-CYB
Function
Produces a transmembrane proton electrochemical gradient as a result of the redox reactions
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Uniprot ID
CY1_HUMAN-CYB_HUMAN
TTD ID
T07569
Drug(s) of This Target
1 Tafenoquine  Drug Info  Approved Malaria
References
Reference 1 Tafenoquine: First Global Approval.Drugs. 2018 Sep;78(14):1517-1523.
Cite NPCDR
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Correspondence

X. N. Sun, Y. T. Zhang, Y. Zhou, X. C. Lian, L. L. Yan, T. Pan, T. Jin, H. Xie, Z. M. Liang, W. Q. Qiu, J. X. Wang, Z. R. Li, F. Zhu*, X. B. Sui*. NPCDR: natural product-based drug combination and its disease-specific molecular regulation. Nucleic Acids Research. 50(D1): 1324-1333 (2020). PMID: 34664659

Prof. Feng ZHU  (zhufeng@zju.edu.cn)

College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China


Prof. Xinbing SUI  (hzzju@hznu.edu.cn)

School of Pharmacy and Department of Medical Oncology, the Affiliated Hospital of Hangzhou Normal University, Hangzhou Normal University, Hangzhou, China