Molecule Details
| General Information of the Molecule | ||||
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| Name |
Cannabinoid receptor 2 (CB2)
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| Synonyms |
hCB2; Cannabinoid CB2 receptor; CX5; CB2B; CB2A; CB-2
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| Gene Name |
CNR2
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| Gene ID | ||||
| Sequence |
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILS
SHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTAS VGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCS ELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLD VRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYA LRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC Click to Show/Hide
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| Function |
May function in inflammatory response, nociceptive transmission and bone homeostasis. Heterotrimeric G protein-coupled receptor for endocannabinoid 2-arachidonoylglycerol mediating inhibition of adenylate cyclase.
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| Uniprot ID | ||||
| TC Number | ||||
| Pfam | ||||
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| Natural Product(s) of This Target | ||||
|---|---|---|---|---|
| 1 | Beta caryophyllene | NP Info | Phase 2 | Syzygium aromaticum |
| 2 | Beta caryophyllene | NP Info | Phase 2 | Syzygium aromaticum |
| 3 | Gegen Qinlian decoction | NP Info | . | Not Available |
| 4 | Gegen Qinlian decoction | NP Info | . | Not Available |
| Drug(s) of This Target | ||||
|---|---|---|---|---|
| 1 | Clarithromycin | Drug Info | Approved | Bacterial infection |
| 2 | Clarithromycin | Drug Info | Approved | Bacterial infection |
| 3 | CPT-11 | Drug Info | . | Not Available |
| 4 | CPT-11 | Drug Info | . | Not Available |
| 5 | N-palmitoylethanolamine | Drug Info | Approved | Attention deficit hyperactivity disorder |
| 6 | N-palmitoylethanolamine | Drug Info | Approved | Attention deficit hyperactivity disorder |