Molecule Details
| General Information of the Molecule | ||||
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| Name |
Pneumocystis carinii Dihydropteroate synthase (PC DHPS)
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| Synonyms |
PC DHPS
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| Gene Name |
PC DHPS
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| Sequence |
MIFKSLKIFPFYQIYGFRFLKGMIFKKKIHLSKLNKNHDLIHIHSLTLKSIVGKNSWAQR
LLQPVVLTLSMGINASLSGNMDDLSYSIDYATVYKEVFKLVENSKFENLLDLSDKISKVV LGDKCKGNWVKVIAETPKGHLLAETGLQIIRRKDGIREIDDQFFIKNLSLYTIIGINPEE RVNKQNIIIDLILFKSSINLECKDDFIINTYNIEKLLKEIVKHVEESTFKTIEALALSIA RISCISHNIEKIIVKVKKSCALAFAESAGVEIVRSRSCFSSNNYIKSENSIDNEAVYISL GSNLGNRIKFILDAIEKMSIKGIKVLKTSMLYESKPMYFKDQPAFYNAVCKVQTSLHPEQ LLFELQLIEKELGRVKVIDKGPRCIDLDIVFYGRKIINSESLIIPHPRVLERSFVLKPLL DISGDLVHPVTGLSIASYFEKIVDHDIKPVLPFLYKNKSIDFSFRSYKAPTYIMAILNLT PDSFFDGGIHSYDSVLIDVEKFINAGATIIDIGGQSTRPGSYIIPLEEEIFRVIPAIKYL QKTYPDILISIDTFRSEVAEQAVKAGASLVNDISGGRYDPKMFNTVARLKVPICIMHMRG NFLNMDNLTDYGTDIIEQITIELEKLLNSAEKSGIPRWNIILDPGLGFSKTLHQNIELLR RFNELKSKNCFNGLPWLLGPSRKRFTGFITGDNMPKDRIWGTVAAVVASISGGCDIIRVH DVYEMYKISKMSDAIWKEIY Click to Show/Hide
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| Function |
Catalyzes three sequential steps of tetrahydrofolate biosynthesis.
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| Uniprot ID | ||||
| Pfam | ||||
| TTD ID | ||||
| Drug(s) of This Target | ||||
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| 1 | Dapsone | Drug Info | Approved | Pneumonia |
| References | ||||
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| Reference 1 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. | |||