| General Information of the Molecule |
| Name |
Estradiol 17 beta-dehydrogenase 1 (17-beta-HSD1)
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| Synonyms |
Short chain dehydrogenase/reductase family 28C member 1; SDR28C1; Placental 17-beta-hydroxysteroid dehydrogenase; Estradiol 17-beta-dehydrogenase 1; EDHB17; EDH17B2; EDH17B1; E2DH; E17KSR; 20-alpha-HSD; 20 alpha-hydroxysteroid dehydrogenase; 17-beta-Hydroxysteroid dehydrogenase type 1; 17-beta-HSD 1
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| Gene Name |
HSD17B1
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| Gene ID |
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| Sequence |
MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL
ETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTV
RMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVH
LSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAEV
FLTALRAPKPTLRYFTTERFLPLLRMRLDDPSGSNYVTAMHREVFGDVPAKAEAGAEAGG
GAGPGAEDEAGRGAVGDPELGDPPAAPQ
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| Function |
Has 20-alpha-HSD activity. Uses preferentially NADH. Favors the reduction of estrogens and androgens.
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| Uniprot ID |
|
| EC Number |
EC: 1.1.1.51
; EC: 1.1.1.62
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| TC Number |
TC: 1.1.1.51; TC: 1.1.1.62
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| Pfam |
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| TTD ID |
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| INTEDE ID |
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