Molecule Details
| General Information of the Molecule | ||||
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| Name |
RNA-binding musashi-2 (MSI2)
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| Synonyms |
RNA-binding protein Musashi-2; RNA-binding protein Musashi homolog 2; Musashi-2
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| Gene Name |
MSI2
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| Gene ID | ||||
| Sequence |
MEANGSQGTSGSANDSQHDPGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKR
SRGFGFVTFADPASVDKVLGQPHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSAN TVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTFENEDVVEKVCEIHFHEINNKMV ECKKAQPKEVMFPPGTRGRARGLPYTMDAFMLGMGMLGYPNFVATYGRGYPGFAPSYGYQ FPGFPAAAYGPVAAAAVAAARGSGSNPARPGGFPGANSPGPVADLYGPASQDSGVGNYIS AASPQPGSGFGHGIAGPLIATAFTNGYH Click to Show/Hide
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| Function |
May play a role in the proliferation and maintenance of stem cells in the central nervous system. RNA binding protein that regulates the expression of target mRNAs at the translation level.
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| Uniprot ID | ||||
| Pfam | ||||
| TTD ID | ||||
| Natural Product(s) of This Target | ||||
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| 1 | Mithramycin A | NP Info | Withdrawn from market | Streptomyces tanashiensis |
| References | ||||
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| Reference 1 | The Pluripotency Factor Musashi-2 Is a Novel Target for Lung Cancer Therapy.Ann Am Thorac Soc. 2018 Apr;15(Supplement_2):S124. | |||