Molecule Details
| General Information of the Molecule | ||||
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| Name |
Signal transducer and activator of transcription 5 (STAT5)
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| Synonyms |
Signal transducer and activator of transcription 5
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| Gene Name |
STAT5A; STAT5B
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| Function |
Involved in cytosolic signalling and in mediating the expression of specific genes. Aberrant STAT5 activity has been shown to be closely connected to a wide range of human cancers, and silencing this aberrant activity is an area of active research in medicinal chemistry.
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| Uniprot ID | ||||
| TTD ID | ||||
| Drug(s) of This Target | ||||
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| 1 | S3I-201 | Drug Info | Investigative | Lupus nephritis |
| References | ||||
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| Reference 1 | A STAT inhibitor patent review: progress since 2011.Expert Opin Ther Pat. 2015;25(12):1397-421. | |||