Molecule Details
| General Information of the Molecule | ||||
|---|---|---|---|---|
| Name |
Microtubule-associated protein (MAP)
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| Synonyms |
Microtubule-associated protein 1; MAP-1
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| Gene Name |
MAP1A; MAP1B
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| Function |
Binds to the tubulin subunits that make up microtubules to regulate their stability. Invovled in stabilizing and destabilizing microtubules, guiding microtubules towards specific cellular locations, cross-linking microtubules and mediating the interactions of microtubules with other proteins in the cell.
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| Uniprot ID | ||||
| TTD ID | ||||
| Natural Product(s) of This Target | ||||
|---|---|---|---|---|
| 1 | Costunolide | NP Info | Investigative | Magnolia sieboldii |
| References | ||||
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| Reference 1 | A sesquiterpene lactone, costunolide, interacts with microtubule protein and inhibits the growth of MCF-7 cells. Chem Biol Interact. 2004 Jan 15;147(1):79-86. | |||