Drug Combination Details
| General Information of the Combination (ID: C02511) | |||||
|---|---|---|---|---|---|
| Name | Fucoidan NP Info | + | Gemcitabine Drug Info | ||
| Structure |
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+ |
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| Disease |
Uterine Sarcoma
[ICD-11: 2B5F]
|
Investigative | [1] | ||
|
Carcinosarcoma
[ICD-11: 2D4Y]
|
Investigative | [1] | |||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
|---|---|---|---|---|---|---|
| α. Enhancing Drug Efficacy by This Combination | ||||||
| Achieving Therapeutic Synergy | Click to Show/Hide | |||||
| Experiment 1 Reporting the Effect of This Combination | [1] | |||||
| In-vitro Model | SK-UT-1 | CVCL_0533 | Uterine corpus leiomyosarcoma | Homo sapiens | ||
| MES-SA | CVCL_1404 | Uterine corpus sarcoma | Homo sapiens | |||
| Experimental
Result(s) |
Isobolographic analysis demonstrates the additive and synergistic effects of gemcitabine combined with fucoidan in uterine sarcomas and carcinosarcoma cells. | |||||
