Drug Combination Details
| General Information of the Combination (ID: C08339) | |||||
|---|---|---|---|---|---|
| Name | Rottlerin NP Info | + | Sorafenib Drug Info | ||
| Structure |
|
+ |
|
||
| Disease |
Brain cancer
[ICD-11: 2A00]
|
Investigative | [1] | ||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
|---|---|---|---|---|---|---|
| α. Enhancing Drug Efficacy by This Combination | ||||||
| Achieving Therapeutic Synergy | Click to Show/Hide | |||||
| Experiment 1 Reporting the Effect of This Combination | [1] | |||||
| Experimental
Result(s) |
Coadministration of sorafenib with rottlerin potently inhibits cell proliferation and migration in human malignant glioma cells. | |||||
| References | ||||
|---|---|---|---|---|
| Reference 1 | Coadministration of sorafenib with rottlerin potently inhibits cell proliferation and migration in human malignant glioma cells. J Pharmacol Exp Ther. 2006 Dec;319(3):1070-80. | |||
