Drug Combination Details
| General Information of the Combination (ID: C08841) | |||||
|---|---|---|---|---|---|
| Name | Rosmarinic acid NP Info | + | Cisplatin Drug Info | ||
| Structure |
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+ |
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| Disease |
Ovarian cancer
[ICD-11: 2C73]
|
Investigative | [1] | ||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
|---|---|---|---|---|---|---|
| α. Reversing Drug Resistance by This Combination | ||||||
| Reversing Drug Resistance | Click to Show/Hide | |||||
| Experiment 1 Reporting the Effect of This Combination | [1] | |||||
| Molecule(s)
Regulation |
Down-regulation | Expression | FOXM1 | Molecule Info |
Pathway MAP
|
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| In-vitro Model | SK-OV-3 | CVCL_0532 | Ovarian serous cystadenocarcinoma | Homo sapiens | ||
| Experimental
Result(s) |
Rosmarinic acid methyl ester regulates ovarian cancer cell migration and reverses cisplatin resistance by inhibiting the expression of forkhead box M1. | |||||
