Drug Combination Details
| General Information of the Combination (ID: C16297) | |||||
|---|---|---|---|---|---|
| Name | Tephrosin NP Info | + | 2-deoxy-D-glucose Drug Info | ||
| Structure |
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+ |
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| Disease |
Cervical cancer
[ICD-11: 2C77]
|
Investigative | [1] | ||
|
Colorectal cancer
[ICD-11: 2B91]
|
Investigative | [1] | |||
|
Lung cancer
[ICD-11: 2C25]
|
Investigative | [1] | |||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
|---|---|---|---|---|---|---|
| α. Enhancing Drug Efficacy by This Combination | ||||||
| Achieving Therapeutic Synergy | Click to Show/Hide | |||||
| Experiment 1 Reporting the Effect of This Combination | [1] | |||||
| In-vitro Model | HeLa | CVCL_0030 | Endocervical adenocarcinoma | Homo sapiens | ||
| HT-29 | CVCL_0320 | Colon adenocarcinoma | Homo sapiens | |||
| SW620 | CVCL_0547 | Colon adenocarcinoma | Homo sapiens | |||
| A-549 | CVCL_0023 | Lung adenocarcinoma | Homo sapiens | |||
| Experimental
Result(s) |
The combination of TSN and 2-DG increased the sensitivity of cancer cells to 2-DG. | |||||
