Drug Combination Details
| General Information of the Combination (ID: C19292) | |||||
|---|---|---|---|---|---|
| Name | Asiaticoside NP Info | + | Ionizing radiation Drug Info | ||
| Structure |
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| Disease |
Healthy individual
[ICD-11: N.A.]
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Investigative | [1] | ||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
|---|---|---|---|---|---|---|
| α. Decreasing Adverse Drug Reaction by This Combination | ||||||
| Decreasing Adverse Drug Reaction | Click to Show/Hide | |||||
| Experiment 1 Reporting the Effect of This Combination | [1] | |||||
| In-vivo Model | C57BL/6J mice (8-10 weeks old, male), which have been shown to be radiation sensitive, were housed five animals per cage under controlled conditions and received standard laboratory diet through the course of the experiment. | |||||
| Experimental
Result(s) |
AC is able to prevent radiation-initiated genotoxicity by mitigating DNA damage. | |||||
| References | ||||
|---|---|---|---|---|
| Reference 1 | Protective Effect of Asiaticoside on Radiation-induced Proliferation Inhibition and DNA Damage of Fibroblasts and Mice Death. Open Life Sci. 2020 Apr 6;15:145-151. | |||
