Drug Combination Details
| General Information of the Combination (ID: C22543) | |||||
|---|---|---|---|---|---|
| Name | Quercetin NP Info | + | Cis-diamminedichloroplatinum Drug Info | ||
| Structure |
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+ |
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| Disease |
Lung cancer
[ICD-11: 2C25]
|
Investigative | [1] | ||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
|---|---|---|---|---|---|---|
| α. Enhancing Drug Efficacy by This Combination | ||||||
| Achieving Therapeutic Synergy | Click to Show/Hide | |||||
| Experiment 1 Reporting the Effect of This Combination | [1] | |||||
| In-vitro Model | LXFL 529L | CVCL_D085 | Lung non-small cell carcinoma | Homo sapiens | ||
| Experimental
Result(s) |
Quercetin enhances the antiproliferative activity of cis-diamminedichloroplatinum (II) in lung cancer cells. | |||||
| References | ||||
|---|---|---|---|---|
| Reference 1 | Enhancement of the antiproliferative activity of cis-diamminedichloroplatinum(II) by quercetin. Int J Cancer. 1990 Mar 15;45(3):536-9. | |||
