Drug Combination Details

General Information of the Combination (ID: C27241)
Name Myo-inositol   NP Info  + N-acetyl-S-(N-2-phenethylthiocarbamoyl)-L-cysteine   Drug Info 
Structure +
Disease
Lung cancer [ICD-11: 2C25]
Investigative [1]
Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally
    α. Enhancing Drug Efficacy by This Combination
                 Achieving Therapeutic Synergy     Click to Show/Hide
                    Experiment 1 Reporting the Effect of This Combination [1]
                    In-vivo Model The animal models were established in mice by a mixture of B[a]P plus NNK.
                    Experimental
                    Result(s)		 PEITC-NAC plus MI was significantly more effective than the agents alone.
References
Reference 1 Inhibition of lung tumorigenesis in A/J mice by N-acetyl-S-(N-2-phenethylthiocarbamoyl)-L-cysteine and myo-inositol, individually and in combination. Carcinogenesis. 2002 Sep;23(9):1455-61.
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