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Drug Combination Details

General Information of the Combination (ID: C27783)
Name Retinol   NP Info  + Monodesbutyl benflumetol   Drug Info 
Structure +
Disease
Malaria [ICD-11: 1F40]
Investigative [1]
Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally
    α. Enhancing Drug Efficacy by This Combination
                 Achieving Therapeutic Synergy     Click to Show/Hide
                    Experiment 1 Reporting the Effect of This Combination [1]
                    In-vitro Model Plasmodium falciparum Microorganism model Plasmodium falciparum
                    In-vivo Model Clinical Trial
                    Experimental
                    Result(s)
Monodesbutyl-benflumetol and retinol combination showed synergistic interaction in Plasmodium falciparum.
References
Reference 1 Synergistic interaction between monodesbutyl-benflumetol and retinol in Plasmodium falciparum. Wien Klin Wochenschr. 2007;119(19-20 Suppl 3):53-9.
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Cite NPCDR
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Correspondence

X. N. Sun, Y. T. Zhang, Y. Zhou, X. C. Lian, L. L. Yan, T. Pan, T. Jin, H. Xie, Z. M. Liang, W. Q. Qiu, J. X. Wang, Z. R. Li, F. Zhu*, X. B. Sui*. NPCDR: natural product-based drug combination and its disease-specific molecular regulation. Nucleic Acids Research. 50(D1): 1324-1333 (2020). PMID: 34664659

Prof. Feng ZHU  (zhufeng@zju.edu.cn)

College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China


Prof. Xinbing SUI  (hzzju@hznu.edu.cn)

School of Pharmacy and Department of Medical Oncology, the Affiliated Hospital of Hangzhou Normal University, Hangzhou Normal University, Hangzhou, China