Drug Combination Details
| General Information of the Combination (ID: C31463) | |||||
|---|---|---|---|---|---|
| Name | Schisandrol B NP Info | + | Albendazole Drug Info | ||
| Structure |
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+ |
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| Disease |
Meningoencephalitis
[ICD-11: 1D01]
|
Investigative | [1] | ||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
|---|---|---|---|---|---|---|
| α. Enhancing Drug Efficacy by This Combination | ||||||
| Achieving Therapeutic Synergy | Click to Show/Hide | |||||
| Experiment 1 Reporting the Effect of This Combination | [1] | |||||
| In-vivo Model | Third-stage larvae (L3) were used to infect Sprague-Dawley (SD) rats. | |||||
| Experimental
Result(s) |
Albendazole-schisandrin B co-treatment significantly inhibited inflammasome activation, pyroptosis, and apoptosis. | |||||
| References | ||||
|---|---|---|---|---|
| Reference 1 | Albendazole-Schisandrin B Co-Therapy on Angiostrongylus cantonensis-Induced Meningoencephalitis in Mice. Biomolecules. 2020 Jul 5;10(7):1001. | |||
