Drug Combination Details
| General Information of the Combination (ID: C36721) | |||||
|---|---|---|---|---|---|
| Name | Salicylic acid NP Info | + | Methylene blue Drug Info | ||
| Structure |
|
+ |
|
||
| Disease |
Breast cancer
[ICD-11: 2C60]
|
Investigative | [1] | ||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
|---|---|---|---|---|---|---|
| α. Enhancing Drug Efficacy by This Combination | ||||||
| Achieving Therapeutic Synergy | Click to Show/Hide | |||||
| Experiment 1 Reporting the Effect of This Combination | [1] | |||||
| In-vitro Model | MDA-MB-231 | CVCL_0062 | Breast adenocarcinoma | Homo sapiens | ||
| Experimental
Result(s) |
Cancer cell killing efficiency of MB increases in the combination with SA due to reduction prevention and stabilization of monomeric form of MB. | |||||
| References | ||||
|---|---|---|---|---|
| Reference 1 | Combination photodynamic therapy of human breast cancer using salicylic acid and methylene blue. Spectrochim Acta A Mol Biomol Spectrosc. 2017 Sep 5;184:198-203. | |||
