Drug Combination Details
| General Information of the Combination (ID: C37984) | |||||
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| Name | Ursodeoxycholic acid | + | Amantadine + Biphenyl dimethyl dicarboxylate | ||
| Click to Show/Hide the Each NP or Drug Information of This Combination | |||||
| Name | Ursodeoxycholic acid NP Info | Drug Info | |||
| Structure |
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| Name | Drug Info | ||||
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| Disease |
Hepatitis C virus infection
[ICD-11: 1E51]
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Investigative | [1] | ||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
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| α. Enhancing Drug Efficacy by This Combination | ||||||
| Achieving Therapeutic Synergy | Click to Show/Hide | |||||
| Experiment 1 Reporting the Effect of This Combination | [1] | |||||
| Molecule(s)
Regulation |
Up-regulation | Activity | STAT1 | Molecule Info |
Pathway MAP
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| In-vitro Model | Hep-G2 | CVCL_0027 | Hepatocellular carcinoma | Homo sapiens | ||
| Experimental
Result(s) |
The inhibition of viral gene replication was enhanced by the combination of triple combination of amantadine, ursodeoxycholic acidbip, and henyl dimethyl dicarboxylate. | |||||
