Drug Combination Details

General Information of the Combination (ID: C45594)
Name Epigallocatechin gallate   NP Info  + Tapentadol   Drug Info 
Structure +
Disease
Breast cancer [ICD-11: 2C60]
Investigative [1]
Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally
    α. Enhancing Drug Efficacy by This Combination
                 Augmenting Drug Sensitivity     Click to Show/Hide
                    Experiment 1 Reporting the Effect of This Combination [1]
                    In-vitro Model MDA-MB-231 CVCL_0062 Breast adenocarcinoma Homo sapiens
                    Experimental
                    Result(s)		 EGCG and TAP reduced the proliferation of MDA-MB-231 cells by impairing cell-cycle progression.
References
Reference 1 Shining a Light on the Effects of the Combination of (-)-Epigallocatechin-3-gallate and Tapentadol on the Growth of Human Triple-negative Breast Cancer Cells. In Vivo. Sep-Oct 2019;33(5):1463-1468.
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