Drug Combination Details
| General Information of the Combination (ID: C50210) | |||||
|---|---|---|---|---|---|
| Name | Amentoflavone NP Info | + | Gamma-ray irradiation Drug Info | ||
| Structure |
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+ |
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| Disease |
Healthy individual
[ICD-11: N.A.]
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Investigative | [1] | ||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
|---|---|---|---|---|---|---|
| α. Decreasing Adverse Drug Reaction by This Combination | ||||||
| Decreasing Adverse Drug Reaction | Click to Show/Hide | |||||
| Experiment 1 Reporting the Effect of This Combination | [1] | |||||
| Molecule(s)
Regulation |
Up-regulation | Expression | TNFAIP2 | Molecule Info | ||
| In-vivo Model | Male C57BL/6 mice(18-22g) were exposed to 60Co Gamma-irradiation at a dose of 7.5 Gy or 3 Gy and the dose rate was 1.58 Gy/min | |||||
| Experimental
Result(s) |
AMF is a potential protective agent against radiation injury. | |||||
| References | ||||
|---|---|---|---|---|
| Reference 1 | Amentoflavone protects the hematopoietic system of mice against Gamma-irradiation. Arch Pharm Res. 2019 Nov;42(11):1021-1029. | |||
