| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally |
| α. Enhancing Drug Efficacy by This Combination |
| Achieving Therapeutic Synergy |
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| Experiment 1 Reporting the Effect of This Combination |
[1] |
| In-vitro Model |
MB49 |
CVCL_7076
|
Bladder transitional cell carcinoma |
Mus musculus |
| In-vivo Model |
To establish a syngeneic mouse bladder tumor model, 1 * 106 MB49 cells in 100 uL cold PBS were injected subcutaneously into the right flank of the each C57BL/6 mouse strain. |
Experimental
Result(s) |
Cucurbitacin B and cisplatin induce the cell death pathways in MB49 mouse bladder cancer model. |
