Drug Combination Details
| General Information of the Combination (ID: C62681) | |||||
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| Name | Sanguinarine | + | Streptomycin + Edetic acid | ||
| Click to Show/Hide the Each NP or Drug Information of This Combination | |||||
| Name | Sanguinarine NP Info | Drug Info | |||
| Structure |
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| Disease |
Staphylococcus infection
[ICD-11: 1C41]
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Investigative | [1] | ||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
|---|---|---|---|---|---|---|
| α. Enhancing Drug Efficacy by This Combination | ||||||
| Achieving Therapeutic Synergy | Click to Show/Hide | |||||
| Experiment 1 Reporting the Effect of This Combination | [1] | |||||
| In-vitro Model | Escherichia coli | Microorganism model | Escherichia coli | |||
| Klebsiella pneumoniae | Microorganism model | Klebsiella pneumoniae | ||||
| Experimental
Result(s) |
Three-drug combination of sanguinarine + EDTA + streptomycin showed synergistic activity against almost all the strains, as well as a strong reduction in the effective doses of sanguinarine, EDTA and streptomycin. | |||||
